Primary Renal Synovial Sarcoma - A rare histology

Renal tumours vary from a benign to highly malignant histology. Here we present a 54 yrs male with a heterogeneous large encapsulated cystic lesion in the right kidney upper pole showing areas of solid component and necrosis with no evidence of metastasis or paraneoplastic features. Post Right Radic...

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Detalles Bibliográficos
Autores principales: Krishnappa, Premkumar, keshavamurthy, Mohan, Tabrez, Shakir, Harinatha, Sreeharsha, Aswathaiya, Mohan Balaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574027/
https://www.ncbi.nlm.nih.gov/pubmed/33102100
http://dx.doi.org/10.1016/j.eucr.2020.101402
Descripción
Sumario:Renal tumours vary from a benign to highly malignant histology. Here we present a 54 yrs male with a heterogeneous large encapsulated cystic lesion in the right kidney upper pole showing areas of solid component and necrosis with no evidence of metastasis or paraneoplastic features. Post Right Radical Nephrectomy IHC, showed positive reaction for BCL-2, CD99 and vimentin, suggesting Primary Renal Synovial Sarcoma. The patient was treated with ifosfamide based chemotherapy in view of unpredictable prognosis. We present this case for its rarity and good response to treatment and as a suggestion for differential diagnosis of Renal Cell Carcinoma.

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