Primary Renal Synovial Sarcoma - A rare histology

Renal tumours vary from a benign to highly malignant histology. Here we present a 54 yrs male with a heterogeneous large encapsulated cystic lesion in the right kidney upper pole showing areas of solid component and necrosis with no evidence of metastasis or paraneoplastic features. Post Right Radic...

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Autores principales: Krishnappa, Premkumar, keshavamurthy, Mohan, Tabrez, Shakir, Harinatha, Sreeharsha, Aswathaiya, Mohan Balaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574027/
https://www.ncbi.nlm.nih.gov/pubmed/33102100
http://dx.doi.org/10.1016/j.eucr.2020.101402
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author Krishnappa, Premkumar
keshavamurthy, Mohan
Tabrez, Shakir
Harinatha, Sreeharsha
Aswathaiya, Mohan Balaiah
author_facet Krishnappa, Premkumar
keshavamurthy, Mohan
Tabrez, Shakir
Harinatha, Sreeharsha
Aswathaiya, Mohan Balaiah
author_sort Krishnappa, Premkumar
collection PubMed
description Renal tumours vary from a benign to highly malignant histology. Here we present a 54 yrs male with a heterogeneous large encapsulated cystic lesion in the right kidney upper pole showing areas of solid component and necrosis with no evidence of metastasis or paraneoplastic features. Post Right Radical Nephrectomy IHC, showed positive reaction for BCL-2, CD99 and vimentin, suggesting Primary Renal Synovial Sarcoma. The patient was treated with ifosfamide based chemotherapy in view of unpredictable prognosis. We present this case for its rarity and good response to treatment and as a suggestion for differential diagnosis of Renal Cell Carcinoma.
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spelling pubmed-75740272020-10-23 Primary Renal Synovial Sarcoma - A rare histology Krishnappa, Premkumar keshavamurthy, Mohan Tabrez, Shakir Harinatha, Sreeharsha Aswathaiya, Mohan Balaiah Urol Case Rep Oncology Renal tumours vary from a benign to highly malignant histology. Here we present a 54 yrs male with a heterogeneous large encapsulated cystic lesion in the right kidney upper pole showing areas of solid component and necrosis with no evidence of metastasis or paraneoplastic features. Post Right Radical Nephrectomy IHC, showed positive reaction for BCL-2, CD99 and vimentin, suggesting Primary Renal Synovial Sarcoma. The patient was treated with ifosfamide based chemotherapy in view of unpredictable prognosis. We present this case for its rarity and good response to treatment and as a suggestion for differential diagnosis of Renal Cell Carcinoma. Elsevier 2020-09-06 /pmc/articles/PMC7574027/ /pubmed/33102100 http://dx.doi.org/10.1016/j.eucr.2020.101402 Text en © 2020 The Author http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Krishnappa, Premkumar
keshavamurthy, Mohan
Tabrez, Shakir
Harinatha, Sreeharsha
Aswathaiya, Mohan Balaiah
Primary Renal Synovial Sarcoma - A rare histology
title Primary Renal Synovial Sarcoma - A rare histology
title_full Primary Renal Synovial Sarcoma - A rare histology
title_fullStr Primary Renal Synovial Sarcoma - A rare histology
title_full_unstemmed Primary Renal Synovial Sarcoma - A rare histology
title_short Primary Renal Synovial Sarcoma - A rare histology
title_sort primary renal synovial sarcoma - a rare histology
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574027/
https://www.ncbi.nlm.nih.gov/pubmed/33102100
http://dx.doi.org/10.1016/j.eucr.2020.101402
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AT keshavamurthymohan primaryrenalsynovialsarcomaararehistology
AT tabrezshakir primaryrenalsynovialsarcomaararehistology
AT harinathasreeharsha primaryrenalsynovialsarcomaararehistology
AT aswathaiyamohanbalaiah primaryrenalsynovialsarcomaararehistology

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