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Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice

BACKGROUND: Gut dysbiosis due to the adverse effects of antibiotics affects outcomes of lung infection. Previous murine models relied on significant depletion of both gut and lung microbiota, rendering the analysis of immune gut-lung cross-talk difficult. Here, we study the effects of antibiotic-ind...

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Detalles Bibliográficos
Autores principales: Dessein, Rodrigue, Bauduin, Marvin, Grandjean, Teddy, Le Guern, Rémi, Figeac, Martin, Beury, Delphine, Faure, Karine, Faveeuw, Christelle, Guery, Benoit, Gosset, Philippe, Kipnis, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574210/
https://www.ncbi.nlm.nih.gov/pubmed/33076936
http://dx.doi.org/10.1186/s13054-020-03320-8