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Sex, androgens and regulation of pulmonary AR, TMPRSS2 and ACE2
The sex discordance in COVID-19 outcomes has been widely recognized, with males generally faring worse than females and a potential link to sex steroids. A plausible mechanism is androgen-induced expression of TMPRSS2 and/or ACE2 in pulmonary tissues that may increase susceptibility or severity in m...
Autores principales: | Baratchian, Mehdi, McManus, Jeffrey M., Berk, Mike, Nakamura, Fumihiko, Mukhopadhyay, Sanjay, Xu, Weiling, Erzurum, Serpil, Drazba, Judy, Peterson, John, Klein, Eric A., Gaston, Ben, Sharifi, Nima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574256/ https://www.ncbi.nlm.nih.gov/pubmed/33083800 http://dx.doi.org/10.1101/2020.04.21.051201 |
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