Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy

BACKGROUND: miR-342-3p, localized to 14q32, is a tumor suppressor miRNA implicated in carcinogenesis. Given the presence of a promotor-associated CpG island for its host gene, EVL, we hypothesized that intronic miR-342-3p is a tumor suppressor co-regulated with host gene by promoter DNA methylation...

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Detalles Bibliográficos
Autores principales: Zhang, Min Yue, Calin, George A., Yuen, Kit San, Jin, Dong Yan, Chim, Chor Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574348/
https://www.ncbi.nlm.nih.gov/pubmed/33076962
http://dx.doi.org/10.1186/s13148-020-00926-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574348/
https://www.ncbi.nlm.nih.gov/pubmed/33076962
http://dx.doi.org/10.1186/s13148-020-00926-1

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