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Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy
BACKGROUND: miR-342-3p, localized to 14q32, is a tumor suppressor miRNA implicated in carcinogenesis. Given the presence of a promotor-associated CpG island for its host gene, EVL, we hypothesized that intronic miR-342-3p is a tumor suppressor co-regulated with host gene by promoter DNA methylation...
Autores principales: | Zhang, Min Yue, Calin, George A., Yuen, Kit San, Jin, Dong Yan, Chim, Chor Sang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574348/ https://www.ncbi.nlm.nih.gov/pubmed/33076962 http://dx.doi.org/10.1186/s13148-020-00926-1 |
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