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Small molecule drug development for rare genodermatoses – evaluation of the current status in epidermolysis bullosa
BACKGROUND: Hereditary epidermolysis bullosa (EB) comprises a heterogeneous group of rare genodermatoses, which are caused by mutations in genes involved in the maintenance of the structural and functional integrity of dermo-epidermal adhesion in various stratified epithelia. In severe variants, gen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574495/ https://www.ncbi.nlm.nih.gov/pubmed/33076941 http://dx.doi.org/10.1186/s13023-020-01467-9 |