Cargando…
What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs
Adenosine-to-inosine (A-to-I) editing is a post-transcriptional modification of RNA which changes its sequence, coding potential and secondary structure. Catalysed by the adenosine deaminase acting on RNA (ADAR) proteins, ADAR1 and ADAR2, A-to-I editing occurs at approximately 50 000–150 000 sites i...
Autores principales: | Heraud-Farlow, Jacki E., Walkley, Carl R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574547/ https://www.ncbi.nlm.nih.gov/pubmed/32603639 http://dx.doi.org/10.1098/rsob.200085 |
Ejemplares similares
-
The majority of A-to-I RNA editing is not required for mammalian homeostasis
por: Chalk, Alistair M., et al.
Publicado: (2019) -
Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes
por: Keegan, Liam P, et al.
Publicado: (2004) -
Generation of a new Adar1p150(−/−) mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis
por: Liang, Zhen, et al.
Publicado: (2023) -
DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA
por: Zheng, Yuxuan, et al.
Publicado: (2017) -
Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo
por: Mendez Ruiz, Shannon, et al.
Publicado: (2023)