Cargando…

Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19

Most of the nations with deplorable health conditions lack rapid COVID-19diagnostic test due to limited testing kits and laboratories. The un-diagnosticmild cases (who show no critical sign and symptoms) play the role as a route that spread the infection unknowingly to healthy individuals. In this p...

Descripción completa

Detalles Bibliográficos
Autores principales: Baba, Isa Abdullahi, Nasidi, Bashir Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574709/
https://www.ncbi.nlm.nih.gov/pubmed/33100604
http://dx.doi.org/10.1016/j.chaos.2020.110374
_version_ 1783597678800666624
author Baba, Isa Abdullahi
Nasidi, Bashir Ahmad
author_facet Baba, Isa Abdullahi
Nasidi, Bashir Ahmad
author_sort Baba, Isa Abdullahi
collection PubMed
description Most of the nations with deplorable health conditions lack rapid COVID-19diagnostic test due to limited testing kits and laboratories. The un-diagnosticmild cases (who show no critical sign and symptoms) play the role as a route that spread the infection unknowingly to healthy individuals. In this paper, we present a fractional order SIR model incorporating individual with mild cases as a compartment to become SMIR model. The existence of the solutions of the model is investigated by solving the fractional Gronwall's inequality using the Laplace transform approach. The equilibrium solutions (DFE & Endemic) are found to be locally asymptotically stable, and subsequently the basic reproduction number is obtained. Also the global stability analysis is carried out by constructing Lyapunov function. Lastly, numerical simulations that support analytic solution follow. It was also shown that when the rate of infection of the mild cases increases, there is equivalent increase in the overall population of infected individuals. Hence to curtail the spread of the disease there is need to take care of the Mild cases as well.
format Online
Article
Text
id pubmed-7574709
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-75747092020-10-21 Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19 Baba, Isa Abdullahi Nasidi, Bashir Ahmad Chaos Solitons Fractals Article Most of the nations with deplorable health conditions lack rapid COVID-19diagnostic test due to limited testing kits and laboratories. The un-diagnosticmild cases (who show no critical sign and symptoms) play the role as a route that spread the infection unknowingly to healthy individuals. In this paper, we present a fractional order SIR model incorporating individual with mild cases as a compartment to become SMIR model. The existence of the solutions of the model is investigated by solving the fractional Gronwall's inequality using the Laplace transform approach. The equilibrium solutions (DFE & Endemic) are found to be locally asymptotically stable, and subsequently the basic reproduction number is obtained. Also the global stability analysis is carried out by constructing Lyapunov function. Lastly, numerical simulations that support analytic solution follow. It was also shown that when the rate of infection of the mild cases increases, there is equivalent increase in the overall population of infected individuals. Hence to curtail the spread of the disease there is need to take care of the Mild cases as well. Elsevier Ltd. 2021-01 2020-10-20 /pmc/articles/PMC7574709/ /pubmed/33100604 http://dx.doi.org/10.1016/j.chaos.2020.110374 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Baba, Isa Abdullahi
Nasidi, Bashir Ahmad
Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title_full Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title_fullStr Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title_full_unstemmed Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title_short Fractional Order Model for the Role of Mild Cases in the Transmission of COVID-19
title_sort fractional order model for the role of mild cases in the transmission of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574709/
https://www.ncbi.nlm.nih.gov/pubmed/33100604
http://dx.doi.org/10.1016/j.chaos.2020.110374
work_keys_str_mv AT babaisaabdullahi fractionalordermodelfortheroleofmildcasesinthetransmissionofcovid19
AT nasidibashirahmad fractionalordermodelfortheroleofmildcasesinthetransmissionofcovid19