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CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos

OBJECTIVES: DNA damage and errors of accurate chromosome segregation lead to aneuploidy and foetal defects. DNA repair and the spindle assembly checkpoint (SAC) are the mechanisms developed to protect from these defects. Checkpoint kinase 1 (CHK1) is reported to be an important DNA damage response p...

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Detalles Bibliográficos
Autores principales:	Ju, Jia‐Qian, Li, Xiao‐Han, Pan, Meng‐Hao, Xu, Yao, Sun, Ming‐Hong, Xu, Yi, Sun, Shao‐Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574881/ https://www.ncbi.nlm.nih.gov/pubmed/32914523 http://dx.doi.org/10.1111/cpr.12895

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