Cargando…
Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications
Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane microdomains (“lipid rafts”) and play important roles in the modulation of membrane proteins and ion channels, in cell signal...
Autores principales: | Sipione, Simonetta, Monyror, John, Galleguillos, Danny, Steinberg, Noam, Kadam, Vaibhavi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574889/ https://www.ncbi.nlm.nih.gov/pubmed/33117120 http://dx.doi.org/10.3389/fnins.2020.572965 |
Ejemplares similares
-
Naïve Huntington’s disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1
por: Steinberg, Noam, et al.
Publicado: (2023) -
Anti-inflammatory role of GM1 and other gangliosides on microglia
por: Galleguillos, Danny, et al.
Publicado: (2022) -
In-Cell Labeling Coupled to Direct Analysis of Extracellular Vesicles in the Conditioned Medium to Study Extracellular Vesicles Secretion with Minimum Sample Processing and Particle Loss
por: Viveiros, Anissa, et al.
Publicado: (2022) -
Disease‐modifying effects of ganglioside GM1 in Huntington's disease models
por: Alpaugh, Melanie, et al.
Publicado: (2017) -
Gangliosides: Treatment Avenues in Neurodegenerative Disease
por: Magistretti, Pierre J., et al.
Publicado: (2019)