Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

Many unknowns exist about human immune responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4(+) T cells have been reported in unexposed individuals, suggesting preexisting cross-reactive T cell memory in 20 to 50% of people. However, the source...

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Detalles Bibliográficos
Autores principales: Mateus, Jose, Grifoni, Alba, Tarke, Alison, Sidney, John, Ramirez, Sydney I., Dan, Jennifer M., Burger, Zoe C., Rawlings, Stephen A., Smith, Davey M., Phillips, Elizabeth, Mallal, Simon, Lammers, Marshall, Rubiro, Paul, Quiambao, Lorenzo, Sutherland, Aaron, Yu, Esther Dawen, da Silva Antunes, Ricardo, Greenbaum, Jason, Frazier, April, Markmann, Alena J., Premkumar, Lakshmanane, de Silva, Aravinda, Peters, Bjoern, Crotty, Shane, Sette, Alessandro, Weiskopf, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574914/
https://www.ncbi.nlm.nih.gov/pubmed/32753554
http://dx.doi.org/10.1126/science.abd3871

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