Cargando…

Single-cell analysis reveals immune modulation and metabolic switch in tumor-draining lymph nodes

Lymph-node metastasis is a prognosis factor for poor clinical outcome of breast cancer patients. Currently, how breast cancer cells establish pre-metastatic niche in the tumor-draining lymph nodes (TDLNs) is still unclear. To address this question, we isolated heterogeneous cells including immune an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yen-Liang, Chen, Chung-Hsing, Chen, Jing-Yi, Lai, You-Syuan, Wang, Shao-Chun, Jiang, Shih-Sheng, Hung, Wen-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575008/ https://www.ncbi.nlm.nih.gov/pubmed/33117603 http://dx.doi.org/10.1080/2162402X.2020.1830513

Ejemplares similares

slanDCs in carcinoma-draining lymph nodes
por: Vermi, William, et al.
Publicado: (2014)

Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma
por: Riedel, Angela, et al.
Publicado: (2022)

Unlocking the therapeutic potential of primary tumor-draining lymph nodes
por: Rotman, Jossie, et al.
Publicado: (2019)

Immune Checkpoint Therapy: Tumor Draining Lymph Nodes in the Spotlights
por: Fransen, Marieke F., et al.
Publicado: (2021)

STUDIES OF THE CELLS IN THE AFFERENT AND EFFERENT LYMPH OF LYMPH NODES DRAINING THE SITE OF SKIN HOMOGRAFTS
por: Hall, J. G.
Publicado: (1967)

Immunological significance of the morphological changes in lymph nodes draining breast cancer.
por: Anastassiades, O. T., et al.
Publicado: (1966)

Reactions in Lymph Nodes Draining X-Irradiated and Carcinogen Treated Tissues
por: Marshall, A. H. E.
Publicado: (1956)

The Draining Lymph Node in Rheumatoid Arthritis: Current Concepts and Research Perspectives
por: Benaglio, Francesca, et al.
Publicado: (2015)

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes
por: Commerford, Catharina D., et al.
Publicado: (2018)

Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes
por: Blobner, Jens, et al.
Publicado: (2021)

Kidney-Draining Lymph Node Fibrosis Following Unilateral Ureteral Obstruction
por: Li, Xiaofei, et al.
Publicado: (2021)

39607 Mapping the Draining Lymph Nodes in Central Nervous System Malignancies
por: Coxon, Andrew T., et al.
Publicado: (2021)

Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis
por: Mohammed, Sulma I, et al.
Publicado: (2020)

Metinel Node—The First Lymph Node Draining a Metastasis—Contains Tumor-Reactive Lymphocytes
por: Dahl, Kjell, et al.
Publicado: (2008)

Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections()()
por: Lawton, Jennifer C., et al.
Publicado: (2014)

Reprogramming of sentinel lymph node microenvironment during tumor metastasis
por: Li, Yen-Liang, et al.
Publicado: (2022)

Microenvironment of Tumor-Draining Lymph Nodes: Opportunities for Liposome-Based Targeted Therapy
por: Chandrasekaran, Siddarth, et al.
Publicado: (2014)

COX-2 Inhibition Reduces Brucella Bacterial Burden in Draining Lymph Nodes
por: Gagnaire, Aurélie, et al.
Publicado: (2016)

Characterization of Antigen-Presenting Cell Subsets in Human Liver-Draining Lymph Nodes
por: Boor, Patrick P. C., et al.
Publicado: (2019)

Vaccine-draining lymph nodes of cancer patients for generating anti-cancer antibodies
por: Shukla, Girja S., et al.
Publicado: (2017)

Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors
por: Zhao, Xianda, et al.
Publicado: (2020)

Suction Drain Volume following Axillary Lymph Node Dissection for Melanoma—When to Remove Drains? A Retrospective Cohort Study
por: Winter, Raimund, et al.
Publicado: (2022)

Quantitative, Architectural Analysis of Immune Cell Subsets in Tumor-Draining Lymph Nodes from Breast Cancer Patients and Healthy Lymph Nodes
por: Setiadi, A. Francesca, et al.
Publicado: (2010)

Pancreatic draining lymph nodes (PLNs) serve as a pathogenic hub contributing to the development of type 1 diabetes
por: Sun, Fei, et al.
Publicado: (2023)

Pivotal roles of tumor‐draining lymph nodes in the abscopal effects from combined immunotherapy and radiotherapy
por: Liu, Zhaoyun, et al.
Publicado: (2022)

Advanced ovarian cancer: Vaccination site draining lymph node as target of immuno-modulative adjuvants in autologous cancer vaccine
por: Lasalvia-Prisco, Eduardo, et al.
Publicado: (2007)

Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer
por: He, Miao, et al.
Publicado: (2023)

The Strategy of T Cell Antigen-presenting Cell Encounter in Antigen-draining Lymph Nodes Revealed by Imaging of Initial T Cell Activation
por: Bajénoff, Marc, et al.
Publicado: (2003)

Human stomach carcinoma-specific T cells derived from the tumour-draining lymph nodes.
por: Stulle, K., et al.
Publicado: (1994)

Regulation of Dendritic Cell Migration to the Draining Lymph Node: Impact on T Lymphocyte Traffic and Priming
por: Martín-Fontecha, Alfonso, et al.
Publicado: (2003)

Accumulation of Immature Langerhans Cells in Human Lymph Nodes Draining Chronically Inflamed Skin
por: Geissmann, F., et al.
Publicado: (2002)

Distinct mechanisms of B and T lymphocyte accumulation generate tumor-draining lymph node hypertrophy
por: Habenicht, Lauren M., et al.
Publicado: (2016)

Disrupted fibroblastic reticular cells and interleukin-7 expression in tumor draining lymph nodes
por: Gao, Jianbao, et al.
Publicado: (2017)

Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy
por: Buchwald, Zachary S, et al.
Publicado: (2020)

Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients
por: Núñez, Nicolas Gonzalo, et al.
Publicado: (2020)

Migratory dendritic cells in skin-draining lymph nodes have nickel-binding capabilities
por: Kuroishi, Toshinobu, et al.
Publicado: (2020)

Ultrasonographic Algorithm for the Assessment of Sentinel Lymph Nodes That Drain the Mammary Carcinomas in Female Dogs
por: Stan, Florin, et al.
Publicado: (2020)

Vaccinia Virus Infection Inhibits Skin Dendritic Cell Migration to the Draining Lymph Node
por: Aggio, Juliana Bernardi, et al.
Publicado: (2021)

Lymph Nodes Draining Infections Investigated by PET and Immunohistochemistry in a Juvenile Porcine Model
por: Afzelius, Pia, et al.
Publicado: (2022)

IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes
por: Hussain, Timon, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0afk9omp4t992sj0bn60lbeu40