Converting networks to predictive logic models from perturbation signalling data with CellNOpt

SUMMARY: The molecular changes induced by perturbations such as drugs and ligands are highly informative of the intracellular wiring. Our capacity to generate large datasets is increasing steadily. A useful way to extract mechanistic insight from the data is by integrating them with a prior knowledg...

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Detalles Bibliográficos
Autores principales: Gjerga, Enio, Trairatphisan, Panuwat, Gabor, Attila, Koch, Hermann, Chevalier, Celine, Ceccarelli, Franceco, Dugourd, Aurelien, Mitsos, Alexander, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575044/
https://www.ncbi.nlm.nih.gov/pubmed/32516357
http://dx.doi.org/10.1093/bioinformatics/btaa561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575044/
https://www.ncbi.nlm.nih.gov/pubmed/32516357
http://dx.doi.org/10.1093/bioinformatics/btaa561

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