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Converting networks to predictive logic models from perturbation signalling data with CellNOpt
SUMMARY: The molecular changes induced by perturbations such as drugs and ligands are highly informative of the intracellular wiring. Our capacity to generate large datasets is increasing steadily. A useful way to extract mechanistic insight from the data is by integrating them with a prior knowledg...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575044/ https://www.ncbi.nlm.nih.gov/pubmed/32516357 http://dx.doi.org/10.1093/bioinformatics/btaa561 |