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Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques

BACKGROUND. To overcome organ shortage, some centers accept hearts from cardiocirculatory determined death (DCD) donors for heart transplantation (HTx). DCD-HTx is attached with special ethical conflicts on the donor, family, and recipient side. Ethically motivated decisions also have to be made con...

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Autores principales: Saemann, Lars, Karck, Matthias, Korkmaz-Icöz, Sevil, Wenzel, Folker, Szabó, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575185/
https://www.ncbi.nlm.nih.gov/pubmed/33134493
http://dx.doi.org/10.1097/TXD.0000000000001075
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author Saemann, Lars
Karck, Matthias
Korkmaz-Icöz, Sevil
Wenzel, Folker
Szabó, Gábor
author_facet Saemann, Lars
Karck, Matthias
Korkmaz-Icöz, Sevil
Wenzel, Folker
Szabó, Gábor
author_sort Saemann, Lars
collection PubMed
description BACKGROUND. To overcome organ shortage, some centers accept hearts from cardiocirculatory determined death (DCD) donors for heart transplantation (HTx). DCD-HTx is attached with special ethical conflicts on the donor, family, and recipient side. Ethically motivated decisions also have to be made considering organ preservation techniques. However, ethical decision diagrams, which can be applied to find a final answer on the complex field of ethical questions, have not been developed yet. METHODS. In an interdisciplinary group of clinical ethicists, transplantation surgeons, transplantation researchers, and perfusionists, after review of relevant literature, we focused on crucial ethical aspects on DCD-HTx in general and separated ethical conflicts with regard to the individual perspective of the donor, family, and recipient. RESULTS. The leading aspect of discussion in the donor perspective mainly deals with the standoff period and with the definition of death. The perspective of recipients focuses on the wish to say farewell after the patient is deceased. In the recipient perspective ethical questions regarding organ procurement techniques occur. CONCLUSIONS. Ethical decision-making on DCD-HTx is complex, but it can be processed in a structured way by applying the decision diagrams that we have developed.
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spelling pubmed-75751852020-10-29 Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques Saemann, Lars Karck, Matthias Korkmaz-Icöz, Sevil Wenzel, Folker Szabó, Gábor Transplant Direct Ethics BACKGROUND. To overcome organ shortage, some centers accept hearts from cardiocirculatory determined death (DCD) donors for heart transplantation (HTx). DCD-HTx is attached with special ethical conflicts on the donor, family, and recipient side. Ethically motivated decisions also have to be made considering organ preservation techniques. However, ethical decision diagrams, which can be applied to find a final answer on the complex field of ethical questions, have not been developed yet. METHODS. In an interdisciplinary group of clinical ethicists, transplantation surgeons, transplantation researchers, and perfusionists, after review of relevant literature, we focused on crucial ethical aspects on DCD-HTx in general and separated ethical conflicts with regard to the individual perspective of the donor, family, and recipient. RESULTS. The leading aspect of discussion in the donor perspective mainly deals with the standoff period and with the definition of death. The perspective of recipients focuses on the wish to say farewell after the patient is deceased. In the recipient perspective ethical questions regarding organ procurement techniques occur. CONCLUSIONS. Ethical decision-making on DCD-HTx is complex, but it can be processed in a structured way by applying the decision diagrams that we have developed. Lippincott Williams & Wilkins 2020-10-19 /pmc/articles/PMC7575185/ /pubmed/33134493 http://dx.doi.org/10.1097/TXD.0000000000001075 Text en Copyright © 2020 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Ethics
Saemann, Lars
Karck, Matthias
Korkmaz-Icöz, Sevil
Wenzel, Folker
Szabó, Gábor
Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title_full Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title_fullStr Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title_full_unstemmed Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title_short Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
title_sort ethical decision diagrams on donation after cardiocirculatory death heart transplantation considering organ preservation techniques
topic Ethics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575185/
https://www.ncbi.nlm.nih.gov/pubmed/33134493
http://dx.doi.org/10.1097/TXD.0000000000001075
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