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Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report
Aluminum phosphide is a common suicidal agent in an agrarian country like India. Toxicity is mostly due to the liberation of phosphine gas, which non-competitively inhibits cytochrome oxidase in the mitochondria causing cell hypoxia. It can involve almost any organ in the body, but the most common i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575287/ https://www.ncbi.nlm.nih.gov/pubmed/33101800 http://dx.doi.org/10.7759/cureus.10552 |
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author | Guru, Satyabrata Kumar, Rajesh Behera, Anupama Patra, Subhabrata Kumar, Prakash |
author_facet | Guru, Satyabrata Kumar, Rajesh Behera, Anupama Patra, Subhabrata Kumar, Prakash |
author_sort | Guru, Satyabrata |
collection | PubMed |
description | Aluminum phosphide is a common suicidal agent in an agrarian country like India. Toxicity is mostly due to the liberation of phosphine gas, which non-competitively inhibits cytochrome oxidase in the mitochondria causing cell hypoxia. It can involve almost any organ in the body, but the most common is cardiovascular system. Various cardiovascular manifestations are hypotension, myocarditis, pericarditis, congestive heart failure, various ECG changes like myocardial infarction, conduction abnormalities, various arrhythmias, and very rarely unmasking of the Brugada pattern. Here we are presenting a case in which the patient developed unmasking of the Brugada pattern in ECG, and gradually he improved symptomatically and ECG wise with conservative treatment. As unmasking of the Brugada pattern in ECG can lead to life-threatening arrhythmias, one has to be cautious and keep this in mind while dealing with a case of aluminum phosphide poisoning. |
format | Online Article Text |
id | pubmed-7575287 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-75752872020-10-22 Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report Guru, Satyabrata Kumar, Rajesh Behera, Anupama Patra, Subhabrata Kumar, Prakash Cureus Cardiology Aluminum phosphide is a common suicidal agent in an agrarian country like India. Toxicity is mostly due to the liberation of phosphine gas, which non-competitively inhibits cytochrome oxidase in the mitochondria causing cell hypoxia. It can involve almost any organ in the body, but the most common is cardiovascular system. Various cardiovascular manifestations are hypotension, myocarditis, pericarditis, congestive heart failure, various ECG changes like myocardial infarction, conduction abnormalities, various arrhythmias, and very rarely unmasking of the Brugada pattern. Here we are presenting a case in which the patient developed unmasking of the Brugada pattern in ECG, and gradually he improved symptomatically and ECG wise with conservative treatment. As unmasking of the Brugada pattern in ECG can lead to life-threatening arrhythmias, one has to be cautious and keep this in mind while dealing with a case of aluminum phosphide poisoning. Cureus 2020-09-20 /pmc/articles/PMC7575287/ /pubmed/33101800 http://dx.doi.org/10.7759/cureus.10552 Text en Copyright © 2020, Guru et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Guru, Satyabrata Kumar, Rajesh Behera, Anupama Patra, Subhabrata Kumar, Prakash Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title | Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title_full | Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title_fullStr | Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title_full_unstemmed | Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title_short | Aluminium Phosphide-Induced Expression of Covertly Present Brugada Pattern in Electrocardiogram: A Rare Case Report |
title_sort | aluminium phosphide-induced expression of covertly present brugada pattern in electrocardiogram: a rare case report |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575287/ https://www.ncbi.nlm.nih.gov/pubmed/33101800 http://dx.doi.org/10.7759/cureus.10552 |
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