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Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh

BACKGROUND AND AIMS: This study investigated the clinical manifestations, outcomes and long-term complications of COVID-19 inpatients in southern part of Bangladesh while emphasizing on individuals having diabetes. METHODS: A cross-sectional study was conducted for a sample of COVID-19 inpatients ac...

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Autores principales: Akter, Farhana, Mannan, Adnan, Mehedi, H.M. Hamidullah, Rob, Md. Abdur, Ahmed, Shakeel, Salauddin, Asma, Hossain, Md. Shakhawat, Hasan, Md. Mahbub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Diabetes India. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575434/
https://www.ncbi.nlm.nih.gov/pubmed/33113469
http://dx.doi.org/10.1016/j.dsx.2020.10.016
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author Akter, Farhana
Mannan, Adnan
Mehedi, H.M. Hamidullah
Rob, Md. Abdur
Ahmed, Shakeel
Salauddin, Asma
Hossain, Md. Shakhawat
Hasan, Md. Mahbub
author_facet Akter, Farhana
Mannan, Adnan
Mehedi, H.M. Hamidullah
Rob, Md. Abdur
Ahmed, Shakeel
Salauddin, Asma
Hossain, Md. Shakhawat
Hasan, Md. Mahbub
author_sort Akter, Farhana
collection PubMed
description BACKGROUND AND AIMS: This study investigated the clinical manifestations, outcomes and long-term complications of COVID-19 inpatients in southern part of Bangladesh while emphasizing on individuals having diabetes. METHODS: A cross-sectional study was conducted for a sample of COVID-19 inpatients across four different hospitals of Bangladesh between April 1and June 30, 2020. Variation in clinical characteristics, contact history, comorbidities, treatment patterns, and immediate post COVID complications were investigated. RESULTS: There were 734 COVID-19 presentations in this study of which 19.8% of patients had diabetes and 76% of the COVID-19 patients were male. Among biochemical parameters, plasma glucose, D-dimer, and Troponin-I levels were significantly elevated amidst the cohort with diabetes. The frequency of patients requiring insulin increased threefold during infection with SARS CoV-2. 1.4% patients developed new onset of diabetes mellitus. A number of COVID-19 patients with diabetes have been suffering from complications post-recovery including pain, discomfort, and sleep disturbance. CONCLUSION: Individuals with diabetes have experienced a severe manifestation of COVID-19 and post disease complications. Further in-depth studies focused on larger sample sizes are entailed to assess the relationships elaborately.
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spelling pubmed-75754342020-10-21 Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh Akter, Farhana Mannan, Adnan Mehedi, H.M. Hamidullah Rob, Md. Abdur Ahmed, Shakeel Salauddin, Asma Hossain, Md. Shakhawat Hasan, Md. Mahbub Diabetes Metab Syndr Article BACKGROUND AND AIMS: This study investigated the clinical manifestations, outcomes and long-term complications of COVID-19 inpatients in southern part of Bangladesh while emphasizing on individuals having diabetes. METHODS: A cross-sectional study was conducted for a sample of COVID-19 inpatients across four different hospitals of Bangladesh between April 1and June 30, 2020. Variation in clinical characteristics, contact history, comorbidities, treatment patterns, and immediate post COVID complications were investigated. RESULTS: There were 734 COVID-19 presentations in this study of which 19.8% of patients had diabetes and 76% of the COVID-19 patients were male. Among biochemical parameters, plasma glucose, D-dimer, and Troponin-I levels were significantly elevated amidst the cohort with diabetes. The frequency of patients requiring insulin increased threefold during infection with SARS CoV-2. 1.4% patients developed new onset of diabetes mellitus. A number of COVID-19 patients with diabetes have been suffering from complications post-recovery including pain, discomfort, and sleep disturbance. CONCLUSION: Individuals with diabetes have experienced a severe manifestation of COVID-19 and post disease complications. Further in-depth studies focused on larger sample sizes are entailed to assess the relationships elaborately. Diabetes India. Published by Elsevier Ltd. 2020 2020-10-21 /pmc/articles/PMC7575434/ /pubmed/33113469 http://dx.doi.org/10.1016/j.dsx.2020.10.016 Text en © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Akter, Farhana
Mannan, Adnan
Mehedi, H.M. Hamidullah
Rob, Md. Abdur
Ahmed, Shakeel
Salauddin, Asma
Hossain, Md. Shakhawat
Hasan, Md. Mahbub
Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title_full Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title_fullStr Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title_full_unstemmed Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title_short Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh
title_sort clinical characteristics and short term outcomes after recovery from covid-19 in patients with and without diabetes in bangladesh
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575434/
https://www.ncbi.nlm.nih.gov/pubmed/33113469
http://dx.doi.org/10.1016/j.dsx.2020.10.016
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