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Integrative analysis of key candidate genes and signaling pathways in autoimmune thyroid dysfunction related to anti-CTLA-4 therapy by bioinformatics

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), the first immune checkpoint to be targeted clinically, has provided an effective treatment option for various malignancies. However, the clinical advantages associated with CTLA-4 inhibitors can be offset by the potentially severe immune-related...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Garofano, Francesca, Wu, Xiaolong, Schmid, Matthias, Krawitz, Peter, Essler, Markus, Schmidt-Wolf, Ingo G. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Preclinical Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575511/ https://www.ncbi.nlm.nih.gov/pubmed/32500465 http://dx.doi.org/10.1007/s10637-020-00952-z

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