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Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells

Vascular smooth muscle cell (VSMC) function is regulated by Nox-derived reactive oxygen species (ROS) and redox-dependent signaling in discrete cellular compartments. Whether cholesterol-rich microdomains (lipid rafts/caveolae) are involved in these processes is unclear. Here we examined the sub-cel...

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Detalles Bibliográficos
Autores principales: Anagnostopoulou, Aikaterini, Camargo, Livia L., Rodrigues, Daniel, Montezano, Augusto C., Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575553/
https://www.ncbi.nlm.nih.gov/pubmed/33082354
http://dx.doi.org/10.1038/s41598-020-73751-4