Cargando…

Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers

To evaluate whether radiomic features from contrast-enhanced computed tomography (CE-CT) can identify DNA mismatch repair deficient (MMR-D) and/or tumor mutational burden-high (TMB-H) endometrial cancers (ECs). Patients who underwent targeted massively parallel sequencing of primary ECs between 2014...

Descripción completa

Detalles Bibliográficos
Autores principales:	Veeraraghavan, Harini, Friedman, Claire F., DeLair, Deborah F., Ninčević, Josip, Himoto, Yuki, Bruni, Silvio G., Cappello, Giovanni, Petkovska, Iva, Nougaret, Stephanie, Nikolovski, Ines, Zehir, Ahmet, Abu-Rustum, Nadeem R., Aghajanian, Carol, Zamarin, Dmitriy, Cadoo, Karen A., Diaz, Luis A., Leitao, Mario M., Makker, Vicky, Soslow, Robert A., Mueller, Jennifer J., Weigelt, Britta, Lakhman, Yulia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575573/ https://www.ncbi.nlm.nih.gov/pubmed/33082371 http://dx.doi.org/10.1038/s41598-020-72475-9

Ejemplares similares

Retreatment with carboplatin and paclitaxel for recurrent endometrial cancer: A retrospective study of the Memorial Sloan Kettering Cancer Center experience
por: Rubinstein, Maria, et al.
Publicado: (2019)

Brain metastases in patients with low-grade endometrial carcinoma
por: Cybulska, Paulina, et al.
Publicado: (2018)

Genomic Landscape of Endometrial Carcinomas of No Specific Molecular Profile
por: Momeni-Boroujeni, Amir, et al.
Publicado: (2022)

Pattern of disease and response to pembrolizumab in recurrent cervical cancer
por: Miller, Kathryn M., et al.
Publicado: (2021)

Adjuvant chemotherapy in patients with operable granulosa cell tumors of the ovary: a surveillance, epidemiology, and end results cohort study
por: Oseledchyk, Anton, et al.
Publicado: (2018)

Early disease progression and treatment discontinuation in patients with advanced ovarian cancer receiving immune checkpoint blockade
por: Boland, Julia L., et al.
Publicado: (2018)

Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary
por: Da Cruz Paula, Arnaud, et al.
Publicado: (2020)

Brain metastasis in advanced serous borderline tumor of the ovary: A case presentation()
por: Martin, Madhuri, et al.
Publicado: (2017)

Durvalumab with or without tremelimumab in patients with persistent or recurrent endometrial cancer or endometrial carcinosarcoma: A randomized open-label phase 2 study
por: Rubinstein, Maria M., et al.
Publicado: (2023)

Radiation therapy for epithelial ovarian cancer brain metastases: clinical outcomes and predictors of survival
por: Teckie, Sewit, et al.
Publicado: (2013)

MRI in female pelvis: an ESUR/ESR survey
por: Nougaret, Stephanie, et al.
Publicado: (2022)

Primary myoepithelial carcinoma of the lung: a rare entity treated with parenchymal sparing resection
por: Sarkaria, Inderpal S, et al.
Publicado: (2011)

Predicting endometrial cancer subtypes and molecular features from histopathology images using multi-resolution deep learning models
por: Hong, Runyu, et al.
Publicado: (2021)

Tumor lenvatinib addiction and withdrawal rebound response in patients with advanced endometrial cancer
por: Lam, Clarissa, et al.
Publicado: (2023)

Integrated Multi-Tumor Radio-Genomic Marker of Outcomes in Patients with High Serous Ovarian Carcinoma
por: Veeraraghavan, Harini, et al.
Publicado: (2020)

Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer
por: Boehm, Kevin M., et al.
Publicado: (2022)

Malignant priapism in metastatic prostate cancer: A late event occurring early
por: Barrett-Campbell, Odeth, et al.
Publicado: (2018)

Assessing Histology Structures by Ex Vivo MR Microscopy and Exploring the Link Between MRM-Derived Radiomic Features and Histopathology in Ovarian Cancer
por: Tardieu, Marion, et al.
Publicado: (2022)

Perspectives on Telephone and Video Communication in the Intensive Care Unit during COVID-19
por: Kennedy, Niki R., et al.
Publicado: (2021)

Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
por: Jiménez-Sánchez, Alejandro, et al.
Publicado: (2017)

Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets
por: Friedman, Claire F., et al.
Publicado: (2023)

ESR1 hotspot mutations in endometrial stromal sarcoma with high-grade transformation and endocrine treatment
por: Dessources, Kimberly, et al.
Publicado: (2022)

A Phase Ib/II Study of Lenvatinib and Pembrolizumab in Advanced Endometrial Carcinoma (Study 111/KEYNOTE-146): Long-Term Efficacy and Safety Update
por: Makker, Vicky, et al.
Publicado: (2023)

Accelerated Diffusion-Weighted MRI of Rectal Cancer Using a Residual Convolutional Network
por: Mohammadi, Mohaddese, et al.
Publicado: (2023)

Ovarian cancer mutational processes drive site-specific immune evasion
por: Vázquez-García, Ignacio, et al.
Publicado: (2022)

Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary
por: Kim, Sarah H., et al.
Publicado: (2020)

Retained Mismatch Repair Protein Expression Occurs in Approximately 6% of Microsatellite Instability-High Cancers and is Associated with Missense Mutations in Mismatch Repair Genes.
por: Hechtman, Jaclyn F., et al.
Publicado: (2019)

Comprehensive assessment of germline pathogenic variant detection in tumor-only sequencing
por: Terraf, P., et al.
Publicado: (2022)

Clonal relationship and directionality of progression of synchronous endometrial and ovarian carcinomas in patients with DNA mismatch repair-deficiency associated syndromes
por: Moukarzel, Lea A, et al.
Publicado: (2020)

Sustained response to lenvatinib and pembrolizumab in two patients with KRAS-mutated endometrial mesonephric-like adenocarcinoma
por: Shen, Sherry, et al.
Publicado: (2021)

Palbociclib: an evidence-based review of its potential in the treatment of breast cancer
por: Cadoo, Karen A, et al.
Publicado: (2014)

Letter to the Editor regarding the manuscript entitled: “Prevalence of occult gynecologic malignancy at the time of risk reducing and nonprophylactic surgery in patients with Lynch syndrome” by Lachiewicz et al. (Gynecol Oncol. 2014; 132: 434–437)
por: Soslow, Robert A.
Publicado: (2014)

Learning the meaning of new stimuli increases the cross-correlated activity of prefrontal neurons
por: Nougaret, Simon, et al.
Publicado: (2018)

Nonbacterial thrombotic endocarditis with embolic cerebral vascular accidents in a patient with advanced, recurrent clear cell carcinoma of the ovary: A case report
por: Liang, Lusha W., et al.
Publicado: (2016)

The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas
por: Moukarzel, Lea A., et al.
Publicado: (2021)

Editorial: Health (in)equity - examinations of the role of culture and trust
por: Stefanovska-Petkovska, Miodraga, et al.
Publicado: (2022)

Cross-sectional survey of parental barriers to participation in pediatric participant research registries
por: Slotkowski, Rebecca A., et al.
Publicado: (2022)

Detailed structural elucidation of polyesters and acrylates using Fourier transform mass spectrometry
por: Simonsick, William J., et al.
Publicado: (2008)

A pragmatic approach to carcinomas concurrently involving the endometrium and ovary
por: Murali, Rajmohan, et al.
Publicado: (2018)

A Survey of DICER1 Hotspot Mutations in Ovarian and Testicular Sex Cord-Stromal Tumors
por: Conlon, Niamh, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n2kmjc6u72rk5gcjqrn9i92ogi