Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis

Although acne is the most common human inflammatory skin disease, its pathogenic mechanisms remain incompletely understood. Here we show that GATA6, which is expressed in the upper pilosebaceous unit of normal human skin, is down-regulated in acne. GATA6 controls keratinocyte proliferation and diffe...

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Detalles Bibliográficos
Autores principales: Oulès, Bénédicte, Philippeos, Christina, Segal, Joe, Tihy, Matthieu, Vietri Rudan, Matteo, Cujba, Ana-Maria, Grange, Philippe A., Quist, Sven, Natsuga, Ken, Deschamps, Lydia, Dupin, Nicolas, Donati, Giacomo, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575575/
https://www.ncbi.nlm.nih.gov/pubmed/33082341
http://dx.doi.org/10.1038/s41467-020-18784-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575575/
https://www.ncbi.nlm.nih.gov/pubmed/33082341
http://dx.doi.org/10.1038/s41467-020-18784-z

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