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Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis
Although acne is the most common human inflammatory skin disease, its pathogenic mechanisms remain incompletely understood. Here we show that GATA6, which is expressed in the upper pilosebaceous unit of normal human skin, is down-regulated in acne. GATA6 controls keratinocyte proliferation and diffe...
Autores principales: | Oulès, Bénédicte, Philippeos, Christina, Segal, Joe, Tihy, Matthieu, Vietri Rudan, Matteo, Cujba, Ana-Maria, Grange, Philippe A., Quist, Sven, Natsuga, Ken, Deschamps, Lydia, Dupin, Nicolas, Donati, Giacomo, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575575/ https://www.ncbi.nlm.nih.gov/pubmed/33082341 http://dx.doi.org/10.1038/s41467-020-18784-z |
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