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A retrospective cross-sectional study to determine chirality status of registered medicines in Tanzania
Medicines with a stereogenic center (asymmetric carbon) are mainly present as racemates with a mixture of equal amounts of enantiomers. One enantiomer may be active while the other inactive, alternatively one may produce side-effects and even toxicity. However, there is lack of information on the ch...
Autores principales: | Mwamwitwa, Kissa W., Kaibere, Raphael M., Fimbo, Adam M., Sabitii, Wilber, Ntinginya, Nyanda E., Mmbaga, Blandina T., Shewiyo, Danstan H., Shearer, Morven C., Smith, Andrew D., Kaale, Eliangiringa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575591/ https://www.ncbi.nlm.nih.gov/pubmed/33082444 http://dx.doi.org/10.1038/s41598-020-74932-x |
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