Upregulation of KCNQ1OT1 promotes resistance to stereotactic body radiotherapy in lung adenocarcinoma by inducing ATG5/ATG12-mediated autophagy via miR-372-3p

Stereotactic body radiotherapy (SBRT) has emerged as a standard treatment for non-small-cell lung cancer. However, its therapeutic advantages are limited with the development of SBRT resistance. The SBRT-resistant cell lines (A549/IR and H1975/IR) were established after exposure with hypofractionate...

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Detalles Bibliográficos
Autores principales: He, Huanyu, Song, Xinmao, Yang, Zuozhang, Mao, Yuchi, Zhang, Kunming, Wang, Yuanyuan, Su, Bin, Li, Qiutian, Chen, Hong, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575601/
https://www.ncbi.nlm.nih.gov/pubmed/33082306
http://dx.doi.org/10.1038/s41419-020-03083-8

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