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A novel PET tracer (18)F-deoxy-thiamine: synthesis, metabolic kinetics, and evaluation on cerebral thiamine metabolism status

BACKGROUND: Some neuropsychological diseases are associated with abnormal thiamine metabolism, including Korsakoff–Wernicke syndrome and Alzheimer’s disease. However, in vivo detection of the status of brain thiamine metabolism is still unavailable and needs to be developed. METHODS: A novel PET tra...

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Detalles Bibliográficos
Autores principales:	Wang, Changpeng, Zhang, Siwei, Zou, Yuefei, Ma, Hongzhao, Jiang, Donglang, Sheng, Lei, Sang, Shaoming, Jin, Lirong, Guan, Yihui, Gui, Yuan, Xu, Zhihong, Zhong, Chunjiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575681/ https://www.ncbi.nlm.nih.gov/pubmed/33079296 http://dx.doi.org/10.1186/s13550-020-00710-5

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