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SLE: Novel Postulates for Therapeutic Options

Genetic deficiency in C1q is a strong susceptibility factor for systemic lupus erythematosus (SLE). There are two major hypotheses that potentially explain the role of C1q in SLE. The first postulates that C1q deficiency abrogates apoptotic cell clearance, leading to persistently high loads of poten...

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Detalles Bibliográficos
Autores principales: Hosszu, Kinga K., Valentino, Alisa, Peerschke, Ellinor I., Ghebrehiwet, Berhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575694/
https://www.ncbi.nlm.nih.gov/pubmed/33117397
http://dx.doi.org/10.3389/fimmu.2020.583853