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Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
Histone deacetylases (HDACs) are enzymes that play a key role in regulating gene expression by remodeling chromatin structure. An imbalance of histone acetylation caused by deregulated HDAC expression and activity is known to promote tumor progression in a number of tumor types, including neuroblast...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575710/ https://www.ncbi.nlm.nih.gov/pubmed/33117806 http://dx.doi.org/10.3389/fcell.2020.578770 |