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Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications

Purpose: To describe the visual outcomes and complications following cataract surgery in dry eye disease (DED). Methods: This retrospective study included 668 eyes of 399 patients with DED, who underwent cataract surgery between 2011 and 2019 at our multi-tier ophthalmology hospital network. Based o...

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Autores principales: Donthineni, Pragnya R., Das, Anthony V., Shanbhag, Swapna S., Basu, Sayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575780/
https://www.ncbi.nlm.nih.gov/pubmed/33117835
http://dx.doi.org/10.3389/fmed.2020.575834
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author Donthineni, Pragnya R.
Das, Anthony V.
Shanbhag, Swapna S.
Basu, Sayan
author_facet Donthineni, Pragnya R.
Das, Anthony V.
Shanbhag, Swapna S.
Basu, Sayan
author_sort Donthineni, Pragnya R.
collection PubMed
description Purpose: To describe the visual outcomes and complications following cataract surgery in dry eye disease (DED). Methods: This retrospective study included 668 eyes of 399 patients with DED, who underwent cataract surgery between 2011 and 2019 at our multi-tier ophthalmology hospital network. Based on etiology, they were divided into three groups: cicatrizing conjunctivitis (CC), meibomian gland dysfunction (MGD), and Sjogren's syndrome (SS). The data on demographics, visual impairment, surgical technique, visual outcomes, and complications were collected using an electronic medical record system. Median LogMAR best corrected visual acuity (BCVA) with interquartile range (IQR) was compared using Wilcoxon's rank sum test. Results: The median age at which cataract surgery was performed was 58 (IQR: 47–65) years. Etiology of DED was CC in 279, MGD in 255, and SS in 134 eyes. Most (471) eyes underwent phacoemulsification, under peribulbar anesthesia (548) through a temporal clear corneal incision (209) with foldable intraocular lens implantation (417). The overall median LogMAR BCVA improved from 1.1 (IQR: 0.6–2.1) at baseline to 0.3 (IQR: 0.1–0.7) and 0.1 (IQR: 0–0.65) at 1 and 6 weeks (p < 0.0001) post-operatively. The median 6 weeks post-operative BCVA was 0.3, 0.1, and 0.1 in CC, MGD, and SS, respectively, and significantly better than at baseline (p < 0.0001). The leading cause of sub-optimal vision was corneal scarring (44; 9%), and the most common complication was posterior capsular rupture with vitreous loss (23; 3%). Conclusion: Cataract surgery has good visual outcomes in patients with DED, without any disconcerting rate of complications. Pre-existing keratopathy is the main determinant of the extent of post-operative visual recovery.
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spelling pubmed-75757802020-10-27 Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications Donthineni, Pragnya R. Das, Anthony V. Shanbhag, Swapna S. Basu, Sayan Front Med (Lausanne) Medicine Purpose: To describe the visual outcomes and complications following cataract surgery in dry eye disease (DED). Methods: This retrospective study included 668 eyes of 399 patients with DED, who underwent cataract surgery between 2011 and 2019 at our multi-tier ophthalmology hospital network. Based on etiology, they were divided into three groups: cicatrizing conjunctivitis (CC), meibomian gland dysfunction (MGD), and Sjogren's syndrome (SS). The data on demographics, visual impairment, surgical technique, visual outcomes, and complications were collected using an electronic medical record system. Median LogMAR best corrected visual acuity (BCVA) with interquartile range (IQR) was compared using Wilcoxon's rank sum test. Results: The median age at which cataract surgery was performed was 58 (IQR: 47–65) years. Etiology of DED was CC in 279, MGD in 255, and SS in 134 eyes. Most (471) eyes underwent phacoemulsification, under peribulbar anesthesia (548) through a temporal clear corneal incision (209) with foldable intraocular lens implantation (417). The overall median LogMAR BCVA improved from 1.1 (IQR: 0.6–2.1) at baseline to 0.3 (IQR: 0.1–0.7) and 0.1 (IQR: 0–0.65) at 1 and 6 weeks (p < 0.0001) post-operatively. The median 6 weeks post-operative BCVA was 0.3, 0.1, and 0.1 in CC, MGD, and SS, respectively, and significantly better than at baseline (p < 0.0001). The leading cause of sub-optimal vision was corneal scarring (44; 9%), and the most common complication was posterior capsular rupture with vitreous loss (23; 3%). Conclusion: Cataract surgery has good visual outcomes in patients with DED, without any disconcerting rate of complications. Pre-existing keratopathy is the main determinant of the extent of post-operative visual recovery. Frontiers Media S.A. 2020-10-07 /pmc/articles/PMC7575780/ /pubmed/33117835 http://dx.doi.org/10.3389/fmed.2020.575834 Text en Copyright © 2020 Donthineni, Das, Shanbhag and Basu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Donthineni, Pragnya R.
Das, Anthony V.
Shanbhag, Swapna S.
Basu, Sayan
Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title_full Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title_fullStr Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title_full_unstemmed Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title_short Cataract Surgery in Dry Eye Disease: Visual Outcomes and Complications
title_sort cataract surgery in dry eye disease: visual outcomes and complications
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575780/
https://www.ncbi.nlm.nih.gov/pubmed/33117835
http://dx.doi.org/10.3389/fmed.2020.575834
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