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E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease

Obesity and hyperlipidemia are independent risk factors of chronic kidney disease (CKD). In mice, diet induced obesity accelerates lipogenesis, lipid accumulation, and injury in kidneys. Expression of adenoviral protein, E4orf1, improves glucose clearance and reduces endogenous insulin secretion to...

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Detalles Bibliográficos
Autores principales: Afruza, Rownock, Akheruzzaman, Md, Dhurandhar, Nikhil V., Hegde, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575883/
https://www.ncbi.nlm.nih.gov/pubmed/33102865
http://dx.doi.org/10.1016/j.heliyon.2020.e05261