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E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease
Obesity and hyperlipidemia are independent risk factors of chronic kidney disease (CKD). In mice, diet induced obesity accelerates lipogenesis, lipid accumulation, and injury in kidneys. Expression of adenoviral protein, E4orf1, improves glucose clearance and reduces endogenous insulin secretion to...
Autores principales: | Afruza, Rownock, Akheruzzaman, Md, Dhurandhar, Nikhil V., Hegde, Vijay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575883/ https://www.ncbi.nlm.nih.gov/pubmed/33102865 http://dx.doi.org/10.1016/j.heliyon.2020.e05261 |
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