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Purinergic signalling in liver diseases: Pathological functions and therapeutic opportunities
Extracellular nucleotides, including ATP, are essential regulators of liver function and serve as danger signals that trigger inflammation upon injury. Ectonucleotidases, which are expressed by liver-resident cells and recruited immune cells sequentially hydrolyse nucleotides to adenosine. The nucle...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575885/ https://www.ncbi.nlm.nih.gov/pubmed/33103092 http://dx.doi.org/10.1016/j.jhepr.2020.100165 |