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Purinergic signalling in liver diseases: Pathological functions and therapeutic opportunities

Extracellular nucleotides, including ATP, are essential regulators of liver function and serve as danger signals that trigger inflammation upon injury. Ectonucleotidases, which are expressed by liver-resident cells and recruited immune cells sequentially hydrolyse nucleotides to adenosine. The nucle...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Jia, Jidong, Zhang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575885/
https://www.ncbi.nlm.nih.gov/pubmed/33103092
http://dx.doi.org/10.1016/j.jhepr.2020.100165

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