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Spinal interleukin-6 contributes to central sensitisation and persistent pain hypersensitivity in a model of juvenile idiopathic arthritis
Pain is the most debilitating symptom in juvenile idiopathic arthritis. As pain correlates poorly to the extent of joint pathology, therapies that control joint inflammation are often inadequate as analgesics. We test the hypothesis that juvenile joint inflammation leads to sensitisation of nocicept...
Autores principales: | Kwok, Charlie H.T., Learoyd, Annastazia E, Canet-Pons, Julia, Trang, Tuan, Fitzgerald, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575902/ https://www.ncbi.nlm.nih.gov/pubmed/32791212 http://dx.doi.org/10.1016/j.bbi.2020.08.004 |
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