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Spinal interleukin-6 contributes to central sensitisation and persistent pain hypersensitivity in a model of juvenile idiopathic arthritis

Pain is the most debilitating symptom in juvenile idiopathic arthritis. As pain correlates poorly to the extent of joint pathology, therapies that control joint inflammation are often inadequate as analgesics. We test the hypothesis that juvenile joint inflammation leads to sensitisation of nocicept...

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Detalles Bibliográficos
Autores principales: Kwok, Charlie H.T., Learoyd, Annastazia E, Canet-Pons, Julia, Trang, Tuan, Fitzgerald, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575902/
https://www.ncbi.nlm.nih.gov/pubmed/32791212
http://dx.doi.org/10.1016/j.bbi.2020.08.004

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