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Challenges and strategies of clinical application of CAR-T therapy in the treatment of tumors—a narrative review
Chimeric antigen receptor T-cell (CAR-T) therapy has achieved good therapeutic efficacy in the treatment of hematological malignancies. In August 2017, Novartis Kymriah (CAR-T cells targeting CD19) was approved by the FDA, indicating the real entry of CAR-T cell therapy into clinical applications an...
Autores principales: | Li, Weijing, Wu, Lili, Huang, Chen, Liu, Ruixia, Li, Zheng, Liu, Lihong, Shan, Baoen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575947/ https://www.ncbi.nlm.nih.gov/pubmed/33145312 http://dx.doi.org/10.21037/atm-20-4502 |
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