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Tumor mutation burden and JARID2 gene alteration are associated with short disease-free survival in locally advanced triple-negative breast cancer
BACKGROUND: In locally advanced triple-negative breast cancer (TNBC), patients who did not achieve pathologic complete response (non-pCR) after neoadjuvant chemotherapy develop rapid tumor metastasis. Tumor mutation burden (TMB) is a potential biomarker of cancer therapy, though whether it is applic...
Autores principales: | Zhang, Xiangmei, Li, Jingping, Yang, Qing, Wang, Yanfang, Li, Xinhui, Liu, Yunjiang, Shan, Baoen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576007/ https://www.ncbi.nlm.nih.gov/pubmed/33145271 http://dx.doi.org/10.21037/atm-20-3773 |
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