Unique genomic features and prognostic value of COSMIC mutational signature 4 in lung adenocarcinoma and lung squamous cell carcinoma

BACKGROUND: Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, and prognosis. Among the signatures cataloged at COSMIC, mutational signature 4 has been linked to smoking. However, the distribution of signature 4 in Chinese lu...

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Detalles Bibliográficos
Autores principales: Cai, Xiuyu, Chen, Zhenghe, Deng, Meiling, Li, Zhiyong, Wu, Qianchao, Wei, Jinwang, Dai, Chun, Wang, Guan, Luo, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576056/
https://www.ncbi.nlm.nih.gov/pubmed/33241025
http://dx.doi.org/10.21037/atm-20-5952

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