Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice

We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IORT) in women with early stage breast cancer outside of a clinical trial, as the recently reported TARGIT-A trial does not provide sufficient evidence to conclude that IORT is superior to no radiotherapy.

Detalles Bibliográficos
Autores principales: Sasieni, Peter D., Sawyer, Elinor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576112/
https://www.ncbi.nlm.nih.gov/pubmed/33087894
http://dx.doi.org/10.1038/s41571-020-00444-2
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author Sasieni, Peter D.
Sawyer, Elinor J.
author_facet Sasieni, Peter D.
Sawyer, Elinor J.
author_sort Sasieni, Peter D.
collection PubMed
description We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IORT) in women with early stage breast cancer outside of a clinical trial, as the recently reported TARGIT-A trial does not provide sufficient evidence to conclude that IORT is superior to no radiotherapy.
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spelling pubmed-75761122020-10-21 Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice Sasieni, Peter D. Sawyer, Elinor J. Nat Rev Clin Oncol News & Views We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IORT) in women with early stage breast cancer outside of a clinical trial, as the recently reported TARGIT-A trial does not provide sufficient evidence to conclude that IORT is superior to no radiotherapy. Nature Publishing Group UK 2020-10-21 2020 /pmc/articles/PMC7576112/ /pubmed/33087894 http://dx.doi.org/10.1038/s41571-020-00444-2 Text en © Springer Nature Limited 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle News & Views
Sasieni, Peter D.
Sawyer, Elinor J.
Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title_full Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title_fullStr Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title_full_unstemmed Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title_short Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
title_sort intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576112/
https://www.ncbi.nlm.nih.gov/pubmed/33087894
http://dx.doi.org/10.1038/s41571-020-00444-2
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