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GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal subtype
Pancreatic cystic neoplasms (PCNs) are a heterogeneous group with varying risks of malignancy. To explore the clinical utility of liquid biopsy in cyst type classification, we analyzed the GNAS/KRAS mutations in circulating cell-free DNA (cfDNA) obtained from 57 patients with histologically diagnose...
Autores principales: | Hata, Tatsuo, Mizuma, Masamichi, Motoi, Fuyuhiko, Omori, Yuko, Ishida, Masaharu, Nakagawa, Kei, Hayashi, Hiroki, Morikawa, Takanori, Kamei, Takashi, Furukawa, Toru, Unno, Michiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576136/ https://www.ncbi.nlm.nih.gov/pubmed/33082481 http://dx.doi.org/10.1038/s41598-020-74868-2 |
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