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Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

Gonadotrophin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone, is the main regulator of the reproductive system, acting on gonadotropic cells by binding to the GnRH1 receptor (GnRH1R). The GnRH-GnRH1R system is a promising therapeutic target for maintaining reproductive...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Cheng, Lin, Wang, Wei, Wu, Chao, Yang, Xin, Du, Xiaozhe, Ma, Liang, Qi, Shiqian, Wei, Yuquan, Lu, Zhiliang, Yang, Shengyong, Shao, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576152/
https://www.ncbi.nlm.nih.gov/pubmed/33082324
http://dx.doi.org/10.1038/s41467-020-19109-w