An efficient synthesis tetrazole and oxadiazole analogues of novel 2′-deoxy-C-nucleosides and their antitumor activity

Various tetrazole and oxadiazole C-nucleoside analogues were synthesized starting from pure α- or β-glycosyl-cyanide. The synthesis of glycosyl-cyanide as key precursor was optimized on gram-scale to furnish crystalline starting material for the assembly of C-nucleosides. Oxadizole C-nucleosides wer...

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Detalles Bibliográficos
Autores principales: Penjarla, Srishylam, Kumar Sabui, Subir, Sudhakar Reddy, Dhande, Banerjee, Shyamapada, Yella Reddy, Paidi, Penta, Santhosh, Sanghvi, Yogesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576186/
https://www.ncbi.nlm.nih.gov/pubmed/33098969
http://dx.doi.org/10.1016/j.bmcl.2020.127612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576186/
https://www.ncbi.nlm.nih.gov/pubmed/33098969
http://dx.doi.org/10.1016/j.bmcl.2020.127612

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