A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets

The identification of true substrates of an E3 ligase is biologically important but biochemically difficult. In recent years, several techniques for identifying substrates have been developed, but these approaches cannot exclude indirect ubiquitination or have other limitations. Here we develop an E...

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Detalles Bibliográficos
Autores principales: Watanabe, Masashi, Saeki, Yasushi, Takahashi, Hidehisa, Ohtake, Fumiaki, Yoshida, Yukiko, Kasuga, Yusuke, Kondo, Takeshi, Yaguchi, Hiroaki, Suzuki, Masanobu, Ishida, Hiroki, Tanaka, Keiji, Hatakeyama, Shigetsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576197/
https://www.ncbi.nlm.nih.gov/pubmed/33082525
http://dx.doi.org/10.1038/s42003-020-01328-y

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