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SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts
The effects of two different mitochondrial‐targeted drugs, SS‐31 and NMN, were tested on Old mouse hearts. After treatment with the drugs, individually or Combined, heart function was examined by echocardiography. SS‐31 partially reversed an age‐related decline in diastolic function while NMN fully...
Autores principales: | Whitson, Jeremy A., Bitto, Alessandro, Zhang, Huiliang, Sweetwyne, Mariya T., Coig, Rene, Bhayana, Saakshi, Shankland, Eric G., Wang, Lu, Bammler, Theo K., Mills, Kathryn F., Imai, Shin‐Ichiro, Conley, Kevin E., Marcinek, David J., Rabinovitch, Peter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576234/ https://www.ncbi.nlm.nih.gov/pubmed/32779818 http://dx.doi.org/10.1111/acel.13213 |
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