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Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice
Age‐associated loss of muscle mass and function (sarcopenia) has a profound effect on the quality of life in the elderly. Our previous studies show that CuZnSOD deletion in mice (Sod1 (−/−) mice) recapitulates sarcopenia phenotypes, including elevated oxidative stress and accelerated muscle atrophy,...
Autores principales: | Bhaskaran, Shylesh, Pollock, Natalie, C. Macpherson, Peter, Ahn, Bumsoo, Piekarz, Katarzyna M., Staunton, Caroline A., Brown, Jacob L., Qaisar, Rizwan, Vasilaki, Aphrodite, Richardson, Arlan, McArdle, Anne, Jackson, Malcolm J., Brooks, Susan V., Van Remmen, Holly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576239/ https://www.ncbi.nlm.nih.gov/pubmed/32886862 http://dx.doi.org/10.1111/acel.13225 |
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