HDAC6‐mediated α‐tubulin deacetylation suppresses autophagy and enhances motility of podocytes in diabetic nephropathy

Histone deacetylase 6 (HDAC6) is the specific subtype of HDACs which preferentially located in the cytoplasm, and is crucial in insulin signalling. However, the role of HDAC6 in type 2 diabetic nephropathy (DN) remains undefined. In current study, we observed that HDAC6 was markedly activated in the...

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Detalles Bibliográficos
Autores principales: Liang, Tiantian, Qi, Chunfang, Lai, Yuxiong, Xie, Jianteng, Wang, Huizhen, Zhang, Li, Lin, Ting, Jv, Menglei, Li, Jing, Wang, Yanhui, Zhang, Yifan, Chen, Zujiao, Qiu, Xueqian, Li, Ruizhao, Li, Zhilian, Ye, Zhiming, Liu, Shuangxin, Liang, Xinling, Shi, Wei, Wang, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576268/
https://www.ncbi.nlm.nih.gov/pubmed/32885602
http://dx.doi.org/10.1111/jcmm.15772

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