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Transforming growth factor β‐mediated micromechanics modulates disease progression in primary myelofibrosis

Primary myelofibrosis (PMF) is a Ph‐negative myeloproliferative neoplasm (MPN), characterized by advanced bone marrow fibrosis and extramedullary haematopoiesis. The bone marrow fibrosis results from excessive proliferation of fibroblasts that are influenced by several cytokines in the microenvironm...

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Detalles Bibliográficos
Autores principales: Teodorescu, Patric, Pasca, Sergiu, Jurj, Ancuta, Gafencu, Grigore, Joelsson, Jon‐Petur, Selicean, Sonia, Moldovan, Cristian, Munteanu, Raluca, Onaciu, Anca, Tigu, Adrian‐Bogdan, Buse, Mihail, Zimta, Alina‐Andreea, Stiufiuc, Rares, Petrushev, Bobe, Desmirean, Minodora, Dima, Delia, Vlad, Cristina, Bergthorsson, Jon Thor, Berce, Cristian, Ciurea, Stefan, Ghiaur, Gabriel, Tomuleasa, Ciprian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576271/
https://www.ncbi.nlm.nih.gov/pubmed/32889753
http://dx.doi.org/10.1111/jcmm.15526

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