Autophagy‐Sirt3 axis decelerates hematopoietic aging

Autophagy suppresses mitochondrial metabolism to preserve hematopoietic stem cells (HSCs) in mice. However, the mechanism by which autophagy regulates hematopoietic aging, in particular in humans, has largely been unexplored. Here, we demonstrate that reduction of autophagy in both hematopoietic cel...

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Detalles Bibliográficos
Autores principales: Fang, Yixuan, An, Ni, Zhu, Lingjiang, Gu, Yue, Qian, Jiawei, Jiang, Gaoyue, Zhao, Ruijin, Wei, Wen, Xu, Li, Zhang, Gaochuan, Yao, Xingyun, Yuan, Na, Zhang, Suping, Zhao, Yun, Wang, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576273/
https://www.ncbi.nlm.nih.gov/pubmed/32951306
http://dx.doi.org/10.1111/acel.13232

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