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IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling

The IKK‐related kinases, IKKε and TBK1, have essential roles in innate immunity in part through modifying MYD88 signalling from the Toll‐like receptors to regulate NF‐κB signalling. We investigated the expression and function of IKKε and TBK1, in diffuse large B‐cell lymphoma (DLBCL). DLBCL cell lin...

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Detalles Bibliográficos
Autores principales:	Carr, Matthew, Mamand, Sami, Chapman, Kathryn L., Perrior, Trevor, Wagner, Simon D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576278/ https://www.ncbi.nlm.nih.gov/pubmed/32858764 http://dx.doi.org/10.1111/jcmm.15774

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