Similar burden of pathogenic coding variants in exceptionally long‐lived individuals and individuals without exceptional longevity

Centenarians (exceptionally long‐lived individuals—ELLI) are a unique segment of the population, exhibiting long human lifespan and healthspan, despite generally practicing similar lifestyle habits as their peers. We tested disease‐associated mutation burden in ELLI genomes by determining the burden...

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Detalles Bibliográficos
Autores principales: Gutman, Danielle, Lidzbarsky, Gabriel, Milman, Sofiya, Gao, Tina, Sin-Chan, Patrick, Gonzaga‐Jauregui, Claudia, Deelen, Joris, Shuldiner, Alan R., Barzilai, Nir, Atzmon, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576295/
https://www.ncbi.nlm.nih.gov/pubmed/32860726
http://dx.doi.org/10.1111/acel.13216

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