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Klotho overexpression improves amyloid‐β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease

Alzheimer's disease (AD) is the most prevalent type of dementia, characterized by the presence of amyloid‐β (Aβ) plaques. We previously reported that Klotho lowered Aβ levels in the brain and protected against cognitive deficits in amyloid precursor protein/presenilin 1(APP/PS1) mice. However,...

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Detalles Bibliográficos
Autores principales:	Zhao, Yue, Zeng, Chen‐Ye, Li, Xiao‐Hong, Yang, Ting‐Ting, Kuang, Xi, Du, Jun‐Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576297/ https://www.ncbi.nlm.nih.gov/pubmed/32964663 http://dx.doi.org/10.1111/acel.13239

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