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A mathematic model to reveal delicate cross‐regulation between MAVS/STING, inflammasome and MyD88‐dependent type I interferon signalling

Early type I interferon is essential for antagonizing against malaria infection, which remains a significant global infectious disease. After Plasmodium yoelii YM infection, the activation of MAVS‐, STING‐ and inflammasome‐IRF3‐mediated pathway could trigger the Socs1 expression to inhibit the TLR7‐...

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Detalles Bibliográficos
Autores principales: Cai, Chunmei, Yu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576308/
https://www.ncbi.nlm.nih.gov/pubmed/32885594
http://dx.doi.org/10.1111/jcmm.15768

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