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A mathematic model to reveal delicate cross‐regulation between MAVS/STING, inflammasome and MyD88‐dependent type I interferon signalling
Early type I interferon is essential for antagonizing against malaria infection, which remains a significant global infectious disease. After Plasmodium yoelii YM infection, the activation of MAVS‐, STING‐ and inflammasome‐IRF3‐mediated pathway could trigger the Socs1 expression to inhibit the TLR7‐...
Autores principales: | Cai, Chunmei, Yu, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576308/ https://www.ncbi.nlm.nih.gov/pubmed/32885594 http://dx.doi.org/10.1111/jcmm.15768 |
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